I’ve used other DAO enzymes, particularly by seeking health, and have had zero issues, just histamine relief. My tried and true was sold out, so I decided to give this a shot after promising reviews; but this actually made me feel worse. I’ve tried it on an empty stomach, and 20 minutes before consuming histamine rich foods, as suggested, and I developed allergy-like symptoms, as well as brain fog. It just made me feel off. I even gave it a week, playing around with the timing, and it’s been the same story. Maybe this works for some but, for me, it’s a purchase that I regret and wish I could get my money back on. Read more

I could feel the difference when eating histamine inducing foods. There was a noticeable reduction in symptoms, BUT I had to roughly triple the dose to get those noticeable effects. Have not tried any other brands to compare as they can be very expensive and this one was fairly reasonable, but I had to take more to get an effect so that may offset the savings. However that’s just me Read more

This DAO enzyme works quite well to prevent histamine reactions from food. However, for me personally another brand (which I won't mention here) works even better. I suppose it depends on your level of histamine intolerance and how many HDU's (units) you require for a single dose. For many people, this supplement may be more than adequate. In my experience you don't want to take more DAO than is necessary because it can make you a bit lethargic (similar to the feeling of Benedryl). So, more or more powerful is not always better. I really like the packaging and individual sealed blister packs to prevent exposure to oxygen and the like. If you have problems with histamine intolerance (or think you do), give this one a try. If this supplement does nothing at all, then you probably don't have a lack of DAO enzyme. It's worth the money. Read more

Who would image that healthy foods like avocado, spinach, strawberries, kombucha, canned fish, etc. could have high levels of histamine in them? Certainly not me, until I read about histamine intolerance. The levels of histamine in these foods don't bother most people, but for people whose digestive system has been primed to react to histamine by chronic SIBO, MACS, or other digestive disorder, high histamine foods can cause a lot of bloating, discomfort, flushing, etc. Wait, what? Even some Lactobacilli produce histamine? No wonder I can't take probiotics or drink kombucha anymore! I'd recommend trying HistaHarmony to anyone who gets headaches from red wine, or feels bloated and ill after eating processed meat, cheese, avocado, tomatoes, spinach, or kimchi. Diamine oxidase (DAO) doesn't block histamine receptors the way antihistamines do (that's why antihistamines have so many side effects). Instead, DAO stays in your digestive tract, breaking down the histamine itself. A few years ago, there was only one company (Umbrellux) selling DAO. Nice that we have choices now! For me, HistaHarmony works as well as Umbrellux DAO, NaturDAO, and Histamine Digest, but at a lower price and without fillers. Don't be put off by the tiny pill vs. price - this isn't a case where size matters. Before DAO, I had gotten to the point that I was reacting to all foods, either nauseous, or crampy, or like my guts were going to explode. Two HistaHarmony before every meal (for me that's super fresh meats and veggies, low FODMAP, low histamine, no dairy, no grains, no yeast) lets me be OK after eating. Six HistaHarmony and I can have small amounts of say, red wine or sushi. This both a great relief and has let me feel like less of a food weirdo at social events. If you have food issues, give the Healthy Gut Company products a try. They are all good quality and backed by research. Read more

I have been taking this product before eating higher Histamine foods. I'm having some health issues with Histamine build up. It seems to be working and not noticing any negative side effects. Pills are tiny and easy to swallow. Read more