About Us Recognized leader in the field of natural medicine. Bio-Botanical Research, Inc. was founded in 1987 in response to the needs of physicians addressing opportunistic infections. The following year, Great Smokies Diagnostic Laboratories (now Genova) was sent a sample of Biocidin by a physician and had it tested for sensitivity against bacteria and yeast species. They found that Biocidin was the most powerful inhibitor of pathogenic organisms that they had tested, and that it was equal or more effective than traditional therapies. They began to refer physicians, and soon many practitioners across the country were reporting outstanding clinical results. In response to health care practitioners continued request for effective solutions to address problems associated with intestinal ecology, immune system disregulation and detoxification, a selection of companion products were developed. Today, over 27 years later, Bio-Botanical Research, Inc. is recognized as a leader in the field of natural medicine. Founding director Dr. Rachel Fresco L. Ac., Ph. D. continues to use her extensive background in medical herbology, functional medicine and clinical nutrition to develop innovative specialty products for health professional use. Dr. Fresco is a popular speaker on the topic of biofilms, microbiome balance, and systemic microbial challenges. Please note: Product expires 3 years after printed Manufacture Date